When the Southern Pacific Railroad came through southern Arizona in 1880, the town of Benson was founded. The new town, was located a mile west of the earlier Butterfield Stage Station and became the rail shipping point for the booming new towns of Tombstone and Bisbee to the south.

Benson was named for Judge William S. Benson of California, a friend of Charles Crocker, president of the railroad. Judge Benson spent many years in the mining regions of the West.

The post office was established July 26, 1880 with John Russ serving as postmaster. The Wells Fargo Station was established in Benson in 1885.